Validating a Coarse-Grained Potential Energy Function through Protein Loop Modelling
نویسندگان
چکیده
منابع مشابه
Validating a Coarse-Grained Potential Energy Function through Protein Loop Modelling
Coarse-grained (CG) methods for sampling protein conformational space have the potential to increase computational efficiency by reducing the degrees of freedom. The gain in computational efficiency of CG methods often comes at the expense of non-protein like local conformational features. This could cause problems when transitioning to full atom models in a hierarchical framework. Here, a CG p...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0065770